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Sture Lindegren Selected Research

Monoclonal Antibodies

4/2023Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211.
1/2019Intraperitoneal α-Emitting Radioimmunotherapy with 211At in Relapsed Ovarian Cancer: Long-Term Follow-up with Individual Absorbed Dose Estimations.
12/2017Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model.
3/2016Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates.
4/2013Successful radioimmunotherapy of established syngeneic rat colon carcinoma with 211At-mAb.
1/2012Comparison of therapeutic efficacy and biodistribution of 213Bi- and 211At-labeled monoclonal antibody MX35 in an ovarian cancer model.
12/2011In vivo distribution of avidin-conjugated MX35 and (211)At-labeled, biotinylated poly-L-lysine for pretargeted intraperitoneal α-radioimmunotherapy.
7/2011Pretargeted radioimmunotherapy with α-particle emitting radionuclides.
7/2009Intraperitoneal alpha-particle radioimmunotherapy of ovarian cancer patients: pharmacokinetics and dosimetry of (211)At-MX35 F(ab')2--a phase I study.
11/2006Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab')2.
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Sture Lindegren Research Topics

Disease

39Neoplasms (Cancer)
04/2024 - 05/2002
19Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 09/2003
7Carcinoma (Carcinomatosis)
01/2017 - 10/2007
6Ascites
12/2017 - 11/2005
4Body Weight (Weight, Body)
02/2020 - 04/2013
3Neoplasm Metastasis (Metastasis)
01/2022 - 08/2014
2Prostatic Neoplasms (Prostate Cancer)
02/2024 - 02/2020
2Ovarian Epithelial Carcinoma
01/2023 - 01/2019
2Residual Neoplasm
02/2020 - 11/2015
2Neoplasm Micrometastasis
08/2013 - 09/2003
1Intestinal Perforation
01/2019
1Fatigue
01/2019
1Breast Neoplasms (Breast Cancer)
10/2016
1Weight Loss (Weight Reduction)
04/2013
1Disease Progression
03/2013

Drug/Important Bio-Agent (IBA)

13Monoclonal AntibodiesIBA
04/2023 - 03/2003
12Astatine-211IBA
04/2024 - 10/2007
7211At-labeled monoclonal antibody MX35IBA
01/2021 - 08/2006
7AntibodiesIBA
01/2021 - 09/2003
5Radioisotopes (Radionuclides)IBA
01/2018 - 07/2011
4AstatineIBA
03/2016 - 09/2003
3Immunoconjugates (Immunoconjugate)IBA
03/2016 - 12/2005
2Neoplasm Antigens (Tumor Antigens)IBA
04/2023 - 01/2015
2AntigensIBA
02/2020 - 01/2019
2EpitopesIBA
01/2015 - 09/2003
2Lysine (L-Lysine)FDA Link
12/2011 - 05/2002
1SolutionsIBA
01/2024
1Colloids (Colloid)IBA
01/2023
1Contrast MediaIBA
01/2023
1Thorium Dioxide (Thorotrast)IBA
01/2023
1farletuzumabIBA
01/2021
1Rituximab (Mabthera)FDA Link
01/2021
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
02/2020
1Indicators and Reagents (Reagents)IBA
01/2019
1tanespimycin (17AAG)IBA
10/2016
1TinIBA
03/2016
1Reducing AgentsIBA
08/2014
1HalogensIBA
08/2014
1BR96 monoclonal antibodyIBA
08/2014
1Lutetium-177IBA
08/2014
1Hematoxylin (Haematoxylon)IBA
08/2013
1Eosine Yellowish-(YS) (Eosin)IBA
08/2013
1Lewis Y antigenIBA
04/2013
1procaine isothiocyanate (PRIT)IBA
03/2013
1AvidinIBA
12/2011
1LigandsIBA
07/2011
1N 30IBA
06/2010
1Trastuzumab (Herceptin)FDA Link
10/2007
1Biotin (Vitamin H)FDA Link
09/2003
1poly-d-lysineIBA
09/2003
1SuspensionsIBA
03/2003

Therapy/Procedure

23Radioimmunotherapy
04/2023 - 09/2003
22Therapeutics
04/2024 - 05/2002
9Aftercare (After-Treatment)
02/2020 - 11/2005
4Drug Therapy (Chemotherapy)
01/2023 - 07/2009
2Intravenous Injections
01/2021 - 01/2017
2Catheters
01/2019 - 07/2009
1Castration
02/2020
1Transcutaneous Electric Nerve Stimulation (TENS)
08/2013